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TRIM13 Antibody

ArtNr CSB-PA024450ESR1HU-50ul
Hersteller Cusabio
Menge 50 ul
Quantity options 100 ul 50 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen IHC, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias B cell chronic lymphocytic leukemia tumor suppressor Leu5 antibody,B-cell chronic lymphocytic leukemia tumor suppressor Leu5 antibody,CAR antibody,DLEU5 antibody,E3 ubiquitin-protein ligase TRIM13 antibody,HGNC:9976 antibody,LEU5 antibody,Leukemia associated protein 5 antibody,Leukemia-associated protein 5 antibody,Putative tumor suppressor RFP2 antibody,Ret finger protein 2 antibody,RFP2 antibody,RING finger protein 77 antibody,RNF77 antibody,TRI13_HUMAN antibody,Trim13 antibody,Tripartite motif protein 13 antibody,Tripartite motif-containing protein 13 antibody
Similar products TRIM13, E3 ubiquitin-protein ligase TRIM13 (EC 2.3.2.27) (B-cell chronic lymphocytic leukemia tumor suppressor Leu5) (Leukemia-associated protein 5) (Putative tumor suppressor RFP2) (RING finger protein 77) (RING-type E3 ubiquitin transferase TRIM13) (Ret finger , LEU5 RFP2 RNF77
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Manufacturer - Targets
TRIM13
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias
B cell chronic lymphocytic leukemia tumor suppressor Leu5 antibody, B-cell chronic lymphocytic leukemia tumor suppressor Leu5 antibody, CAR antibody, DLEU5 antibody, E3 ubiquitin-protein ligase TRIM13 antibody, HGNC:9976 antibody, LEU5 antibody, Leukemia associated protein 5 antibody, Leukemia-associated protein 5 antibody, Putative tumor suppressor RFP2 antibody, Ret finger protein 2 antibody, RFP2 antibody, RING finger protein 77 antibody, RNF77 antibody, TRI13_HUMAN antibody, Trim13 antibody, Tripartite motif protein 13 antibody, Tripartite motif-containing protein 13 antibody
Immunogen Species
Human
Immunogen
Recombinant Human E3 ubiquitin-protein ligase TRIM13 protein (40-310AA)
Dilution
ELISA:1:2000-1:10000
IHC:1:20-1:200
Background
E3 ubiquitin ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a set of processes named ER-associated degradation (ERAD). This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins. Enhances ionizing radiation-induced p53/TP53 stability and apoptosis via ubiquitinating MDM2 and AKT1 and decreasing AKT1 kinase activity through MDM2 and AKT1 proteasomal degradation. Regulates ER stress-induced autophagy, and may act as a tumor suppressor.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method
Antigen Affinity Purified
General Research Areas
Cell Biology
Initial Research Areas
Cell Biology
Antigen Species
Human
Antigen
Recombinant Human E3 ubiquitin-protein ligase TRIM13 protein (40-310AA)
Clonality
Polyclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ul
Lieferbar: In stock
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