UBE3A Antibody

ArtNr	CSB-PA025488LA01HU-50ug
Hersteller	Cusabio
Menge	50 ug
Quantity options	100 ug 20 ug 50 ug
Kategorie	Oncology Neuroscience Aging & Neurological Disorders Antibodies By Cell Type Carcinoma Cell Biology Cell Status Immunohistochemistry ELISA Immunofluorescence Autophagy Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ANCR antibody; Angelman syndrome antibody; AS antibody; CTCL tumor antigen se37 2 antibody; CTCL tumor antigen se37-2 antibody; E6 AP antibody; E6AP antibody; E6AP ubiquitin protein ligase antibody; E6AP ubiquitin-protein ligase antibody; EPVE6AP antibody; FLJ26981 antibody; HECT-type ubiquitin transferase E3A antibody; HPVE6A antibody; Human papilloma virus E6 associated protein Angelman syndrome antibody; Human papilloma virus E6 associated protein antibody; Human papillomavirus E6-associated protein antibody; NY REN 54 antigen antibody; Oncogenic protein associated protein E6 AP antibody; Oncogenic protein associated protein E6AP antibody; Oncogenic protein-associated protein E6-AP antibody; Renal carcinoma antigen NY REN 54 antibody; Renal carcinoma antigen NY-REN-54 antibody; UBE 3A antibody; Ube3a antibody; UBE3A protein antibody; UBE3A_HUMAN antibody; Ubiquitin protein ligase E3A antibody; Ubiquitin-protein ligase E3A antibody
Similar products	UBE3A, Ubiquitin-protein ligase E3A (EC 2.3.2.26) (E6AP ubiquitin-protein ligase) (HECT-type ubiquitin transferase E3A) (Human papillomavirus E6-associated protein) (Oncogenic protein-associated protein E6-AP) (Renal carcinoma antigen NY-REN-54), E6AP EPVE6AP HPVE6A
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	UBE3A
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	ANCR antibody; Angelman syndrome antibody; AS antibody; CTCL tumor antigen se37 2 antibody; CTCL tumor antigen se37-2 antibody; E6 AP antibody; E6AP antibody; E6AP ubiquitin protein ligase antibody; E6AP ubiquitin-protein ligase antibody; EPVE6AP antibody; FLJ26981 antibody; HECT-type ubiquitin transferase E3A antibody; HPVE6A antibody; Human papilloma virus E6 associated protein Angelman syndrome antibody; Human papilloma virus E6 associated protein antibody; Human papillomavirus E6-associated protein antibody; NY REN 54 antigen antibody; Oncogenic protein associated protein E6 AP antibody; Oncogenic protein associated protein E6AP antibody; Oncogenic protein-associated protein E6-AP antibody; Renal carcinoma antigen NY REN 54 antibody; Renal carcinoma antigen NY-REN-54 antibody; UBE 3A antibody; Ube3a antibody; UBE3A protein antibody; UBE3A_HUMAN antibody; Ubiquitin protein ligase E3A antibody; Ubiquitin-protein ligase E3A antibody
Immunogen Species	Human
Immunogen	Recombinant Human Ubiquitin-protein ligase E3A protein (83-234AA)
Dilution	ELISA:1:2000-1:10000 IHC:1:20-1:200 IF:1:50-1:200
Background	E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the RAD23A and RAD23B, MCM7 (which is involved in DNA replication), annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B. Catalyzes the high-risk human papilloma virus E6-mediated ubiquitination of p53/TP53, contributing to the neoplastic progression of cells infected by these viruses. Additionally, may function as a cellular quality control ubiquitin ligase by helping the degradation of the cytoplasmic misfolded proteins. Finally, UBE3A also promotes its own degradation in vivo. Plays an important role in the regulation of the circadian clock: involved in the ubiquitination of the core clock component ARNTL/BMAL1, leading to its proteasomal degradation (PubMed:24728990).
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Epigenetics and Nuclear Signaling
Initial Research Areas	Epigenetics and Nuclear Signaling
Antigen Species	Human
Antigen	Recombinant Human Ubiquitin-protein ligase E3A protein (83-234AA)
Clonality	Polyclonal

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Menge: 50 ug

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Lieferung vsl. bis 11.09.2025

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