HINT1 Antibody

HINT1

Adenosine 5' monophosphoramidase antibody; Adenosine 5''-monophosphoramidase antibody; HINT 1 antibody; HINT1 antibody; HINT1_HUMAN antibody; Histidine triad nucleotide binding protein 1 antibody; Histidine triad nucleotide-binding protein 1 antibody; PKCI 1 antibody; PKCI-1 antibody; PKCI1 antibody; PRKCNH1 antibody; Protein kinase C inhibitor 1 antibody; Protein kinase C interacting protein 1 antibody; Protein kinase C-interacting protein 1 antibody

Recombinant Human Histidine triad nucleotide-binding protein 1 protein (2-126AA)

Hydrolyzes purine nucleotide phosphoramidates with a single phosphate group, including adenosine 5'monophosphoramidate (AMP-NH2), adenosine 5'monophosphomorpholidate (AMP-morpholidate) and guanosine 5'monophosphomorpholidate (GMP-morpholidate). Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, as well as Met-AMP, His-AMP and Asp-AMP, lysyl-GMP (GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester. Can also convert adenosine 5'-O-phosphorothioate and guanosine 5'-O-phosphorothioate to the corresponding nucleoside 5'-O-phosphates with concomitant release of hydrogen sulfide. In addition, functions as scaffolding protein that modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex and by the complex formed with MITF and CTNNB1. Modulates p53/TP53 levels and p53/TP53-mediated apoptosis. Modulates proteasomal degradation of target proteins by the SCF (SKP2-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.

>95%, Protein G purified

Epigenetics and Nuclear Signaling

Recombinant Human Histidine triad nucleotide-binding protein 1 protein (2-126AA)