NR1H3 Antibody

ArtNr	CSB-PA619753LA01HU-50ug
Hersteller	Cusabio
Menge	50 ug
Quantity options	100 ug 20 ug 50 ug
Kategorie	Metabolism Cholesterol & Lipid Metabolism Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies Other Lipid\Cholesterol Metabolism Modulators
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Liver X receptor alpha antibody; LXR a antibody; LXRA antibody; NR1H3 antibody; NR1H3_HUMAN antibody; Nuclear receptor subfamily 1 group H member 3 antibody; Oxysterols receptor LXR alpha antibody; Oxysterols receptor LXR-alpha antibody; RLD 1 antibody; RLD1 antibody
Similar products	NR1H3, LXRA, Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear receptor subfamily 1 group H member 3)
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	NR1H3
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	Liver X receptor alpha antibody; LXR a antibody; LXRA antibody; NR1H3 antibody; NR1H3_HUMAN antibody; Nuclear receptor subfamily 1 group H member 3 antibody; Oxysterols receptor LXR alpha antibody; Oxysterols receptor LXR-alpha antibody; RLD 1 antibody; RLD1 antibody
Immunogen Species	Human
Immunogen	Recombinant Human Oxysterols receptor LXR-alpha protein (1-402AA)
Dilution	ELISA:1:2000-1:10000 WB:1:1000-1:5000 IHC:1:20-1:200
Background	Nuclear receptor that exhibits a ligand-dependent transcriptional activation activity (PubMed:19481530, PubMed:25661920). Interaction with retinoic acid receptor (RXR) shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES (By similarity). LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides (By similarity). Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8 (PubMed:19481530). Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity).
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Cardiovascular
Initial Research Areas	Cardiovascular
Antigen Species	Human
Antigen	Recombinant Human Oxysterols receptor LXR-alpha protein (1-402AA)
Clonality	Polyclonal

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Menge: 50 ug

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Lieferung vsl. bis 09.10.2025

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