RNF20 Antibody

ArtNr	CSB-PA736198LA01HU-50ug
Hersteller	Cusabio
Menge	50 ug
Quantity options	100 ug 20 ug 50 ug
Kategorie	Neuroscience Aging & Neurological Disorders Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot ELISA Immunofluorescence Autophagy Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	BRE1 A antibody,BRE1 antibody,BRE1 E3 ubiquitin ligase homolog antibody,BRE1-A antibody,BRE1A antibody,BRE1A_HUMAN antibody,E3 ubiquitin-protein ligase BRE1A antibody,hBRE1 antibody,Homolog of S. cerevisiae BRE1 antibody,RING finger protein 20 antibody,Ring finger protein 20 E3 ubiquitin protein ligase antibody,Rnf20 antibody
Similar products	RNF20, BRE1A, E3 ubiquitin-protein ligase BRE1A (BRE1-A) (hBRE1) (EC 2.3.2.27) (RING finger protein 20) (RING-type E3 ubiquitin transferase BRE1A)
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Manufacturer - Targets	RNF20
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	BRE1 A antibody, BRE1 antibody, BRE1 E3 ubiquitin ligase homolog antibody, BRE1-A antibody, BRE1A antibody, BRE1A_HUMAN antibody, E3 ubiquitin-protein ligase BRE1A antibody, hBRE1 antibody, Homolog of S. cerevisiae BRE1 antibody, RING finger protein 20 antibody, Ring finger protein 20 E3 ubiquitin protein ligase antibody, Rnf20 antibody
Immunogen Species	Human
Immunogen	Recombinant Human E3 ubiquitin-protein ligase BRE1A protein (1-100AA)
Dilution	ELISA:1:2000-1:10000 IHC:1:20-1:200
Background	Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role inb histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B, reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes. Recruited to the MDM2 promoter, probably by being recruited by p53/TP53, and thereby acts as a transcriptional coactivator. Mediates the polyubiquitination of isoform 2 of PA2G4 in cancer cells leading to its proteasome-mediated degradation.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Cell Biology
Initial Research Areas	Cell Biology
Antigen Species	Human
Antigen	Recombinant Human E3 ubiquitin-protein ligase BRE1A protein (1-100AA)
Clonality	Polyclonal

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Menge: 50 ug

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Lieferung vsl. bis 22.01.2026

Express-Lieferung: 3 Tage sparen

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