NHLRC1 Antibody

ArtNr	CSB-PA740936ESR1HU-50ul
Hersteller	Cusabio
Menge	50 ul
Quantity options	100 ul 50 ul
Kategorie	Oncology Neuroscience Aging & Neurological Disorders Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot ELISA Autophagy Primary Antibodies By Organ Heart & Blood Cancer Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, ELISA
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	bA204B7.2 antibody,E3 ubiquitin-protein ligase NHLRC1 antibody,EPM2A antibody,EPM2B antibody,EPM2B gene antibody,Malin antibody,MGC119262 antibody,MGC119264 antibody,MGC119265 antibody,NHL repeat containing 1 antibody,NHL repeat containing E3 ubiquitin protein ligase 1 antibody,NHL repeat containing protein 1 antibody,NHL repeat-containing protein 1 antibody,NHL repeat-containing protein 1 gene antibody,NHLC1_HUMAN antibody,NHLRC 1 antibody,Nhlrc1 antibody
Similar products	NHLRC1, EPM2B, E3 ubiquitin-protein ligase NHLRC1 (EC 2.3.2.27) (Malin) (NHL repeat-containing protein 1) (RING-type E3 ubiquitin transferase NHLRC1)
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, WB; Recommended dilution: WB:1:1000-1:5000
Manufacturer - Targets	NHLRC1
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	bA204B7.2 antibody, E3 ubiquitin-protein ligase NHLRC1 antibody, EPM2A antibody, EPM2B antibody, EPM2B gene antibody, Malin antibody, MGC119262 antibody, MGC119264 antibody, MGC119265 antibody, NHL repeat containing 1 antibody, NHL repeat containing E3 ubiquitin protein ligase 1 antibody, NHL repeat containing protein 1 antibody, NHL repeat-containing protein 1 antibody, NHL repeat-containing protein 1 gene antibody, NHLC1_HUMAN antibody, NHLRC 1 antibody, Nhlrc1 antibody
Immunogen Species	Human
Immunogen	Recombinant Human E3 ubiquitin-protein ligase NHLRC1 protein (1-280AA)
Dilution	ELISA:1:2000-1:10000 WB:1:1000-1:5000
Background	E3 ubiquitin-protein ligase. Together with the phosphatase EPM2A/laforin, appears to be involved in the clearance of toxic polyglucosan and protein aggregates via multiple pathways. In complex with EPM2A/laforin and HSP70, suppresses the cellular toxicity of misfolded proteins by promoting their degradation through the ubiquitin-proteasome system (UPS). Ubiquitinates the glycogen-targeting protein phosphatase subunits PPP1R3C/PTG and PPP1R3D in a laforin-dependent manner and targets them for proteasome-dependent degradation, thus decreasing glycogen accumulation. Polyubiquitinates EPM2A/laforin and ubiquitinates AGL and targets them for proteasome-dependent degradation. Also promotes proteasome-independent protein degradation through the macroautophagy pathway.
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method	Antigen Affinity Purified
General Research Areas	Cell Biology
Initial Research Areas	Cell Biology
Antigen Species	Human
Antigen	Recombinant Human E3 ubiquitin-protein ligase NHLRC1 protein (1-280AA)
Clonality	Polyclonal

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CSB-PA740936ESR1HU-50ul-datasheet.pdf

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Menge: 50 ul

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Lieferung vsl. bis 22.01.2026

Express-Lieferung: 3 Tage sparen

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