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UBR2 Antibody

ArtNr CSB-PA809001LA01HU-50ug
Hersteller Cusabio
Menge 50 ug
Quantity options 100 ug 20 ug 50 ug
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias UBR2 antibody,C6orf133 antibody,KIAA0349 antibody,E3 ubiquitin-protein ligase UBR2 antibody,EC 2.3.2.27 antibody,N-recognin-2 antibody,RING-type E3 ubiquitin transferase UBR2 antibody,Ubiquitin-protein ligase E3-alpha-2 antibody,Ubiquitin-protein ligase E3-alpha-II antibody
Similar products UBR2, E3 ubiquitin-protein ligase UBR2 (EC 2.3.2.27) (N-recognin-2) (RING-type E3 ubiquitin transferase UBR2) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3-alpha-II), C6orf133 KIAA0349
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
ELISA, WB; Recommended dilution: WB:1:1000-1:5000
Manufacturer - Targets
UBR2
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias
UBR2 antibody, C6orf133 antibody, KIAA0349 antibody, E3 ubiquitin-protein ligase UBR2 antibody, EC 2.3.2.27 antibody, N-recognin-2 antibody, RING-type E3 ubiquitin transferase UBR2 antibody, Ubiquitin-protein ligase E3-alpha-2 antibody, Ubiquitin-protein ligase E3-alpha-II antibody
Immunogen Species
Human
Immunogen
Recombinant Human E3 ubiquitin-protein ligase UBR2 protein (101-439AA)
Dilution
ELISA:1:2000-1:10000
WB:1:1000-1:5000
Background
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method
>95%, Protein G purified
General Research Areas
Cell Biology
Initial Research Areas
Cell Biology
Antigen Species
Human
Antigen
Recombinant Human E3 ubiquitin-protein ligase UBR2 protein (101-439AA)
Clonality
Polyclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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