RNF139 Antibody

ArtNr	CSB-PA837849DSR1HU-50ul
Hersteller	Cusabio
Menge	50 ul
Quantity options	100 ul 50 ul
Kategorie	Oncology Neuroscience Aging & Neurological Disorders Antibodies By Cell Type Carcinoma Cell Biology Cell Status Immunohistochemistry ELISA Autophagy Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	RNF139 antibody,TRC8 antibody,E3 ubiquitin-protein ligase RNF139 antibody,EC 2.3.2.27 antibody,RING finger protein 139 antibody,RING-type E3 ubiquitin transferase RNF139 antibody,Translocation in renal carcinoma on chromosome 8 protein antibody
Similar products	RNF139, TRC8, E3 ubiquitin-protein ligase RNF139 (EC 2.3.2.27) (RING finger protein 139) (RING-type E3 ubiquitin transferase RNF139) (Translocation in renal carcinoma on chromosome 8 protein)
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Manufacturer - Targets	RNF139
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	RNF139 antibody, TRC8 antibody, E3 ubiquitin-protein ligase RNF139 antibody, EC 2.3.2.27 antibody, RING finger protein 139 antibody, RING-type E3 ubiquitin transferase RNF139 antibody, Translocation in renal carcinoma on chromosome 8 protein antibody
Immunogen Species	Human
Immunogen	Recombinant Human E3 ubiquitin-protein ligase RNF139 protein (510-664AA)
Dilution	ELISA:1:2000-1:10000 IHC:1:20-1:200
Background	E3-ubiquitin ligase, acts as a negative regulator of the cell proliferation through mechanisms involving G2/M arrest and cell death. Required for MHC class I ubiquitination in cells expressing the cytomegalovirus protein US2 before dislocation from the endoplasmic reticulum (ER). Affects SREBP processing by hindering the SREBP/SCAP complex translocation from the ER to the Golgi, thereby reducing SREBF2 target gene expression. Required for INSIG1 ubiquitination. May be required for EIF3 complex ubiquitination. May function as a signaling receptor.
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method	Antigen Affinity Purified
General Research Areas	Cell Biology
Initial Research Areas	Cell Biology
Antigen Species	Human
Antigen	Recombinant Human E3 ubiquitin-protein ligase RNF139 protein (510-664AA)
Clonality	Polyclonal

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Menge: 50 ul

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Lieferung vsl. bis 22.01.2026

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