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CREBBP Antibody

ArtNr CSB-PA838805LA01HU-50ug
Hersteller Cusabio
Menge 50 ug
Quantity options 100 ug 20 ug 50 ug
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen IF, IHC, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias CBP antibody,CBP_HUMAN antibody,CREB binding protein antibody,CREB-binding protein antibody,Crebbp antibody,Cyclic AMP responsive enhancer binding protein antibody,KAT3A antibody,RSTS antibody,RTS antibody,Rubinstein Taybi syndrome antibody
Similar products CBP, CREBBP, CREB-binding protein (EC 2.3.1.48)
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Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
Manufacturer - Targets
CREBBP
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias
CBP antibody, CBP_HUMAN antibody, CREB binding protein antibody, CREB-binding protein antibody, Crebbp antibody, Cyclic AMP responsive enhancer binding protein antibody, KAT3A antibody, RSTS antibody, RTS antibody, Rubinstein Taybi syndrome antibody
Immunogen Species
Human
Immunogen
Recombinant Human CREB-binding protein (2217-2442AA)
Dilution
ELISA:1:2000-1:10000
IHC:1:20-1:200
IF:1:50-1:200
Background
Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Acetylates PCNA, acetylation promotes removal of chromatin-bound PCNA and its degradation during nucleotide excision repair (NER) (PubMed:24939902).
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method
>95%, Protein G purified
General Research Areas
Epigenetics and Nuclear Signaling
Initial Research Areas
Epigenetics and Nuclear Signaling
Antigen Species
Human
Antigen
Recombinant Human CREB-binding protein (2217-2442AA)
Clonality
Polyclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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