UFD1 Antibody

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Recombinant Human Ubiquitin recognition factor in ER-associated degradation protein 1 protein (1-307AA)

Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures.

Antigen Affinity Purified

Cell Biology

Recombinant Human Ubiquitin recognition factor in ER-associated degradation protein 1 protein (1-307AA)