MED12 Antibody

Polyclonal Antibody

MED12

Activator recruited cofactor 240 kDa component antibody, Activator-recruited cofactor 240 kDa component antibody, ARC240 antibody, CAG repeat protein 45 antibody, CAGH45 antibody, HOPA antibody, KIAA0192 antibody, MED12 antibody, MED12_HUMAN antibody, Mediator complex subunit 12 antibody, Mediator of RNA polymerase II transcription subunit 12 antibody, OPA containing protein antibody, OPA-containing protein antibody, Thyroid hormone receptor associated protein complex 230 kDa component antibody, Thyroid hormone receptor-associated protein complex 230 kDa component antibody, TNRC11 antibody, Trap230 antibody, Trinucleotide repeat containing gene 11 protein antibody, Trinucleotide repeat-containing gene 11 protein antibody

Recombinant Human Mediator of RNA polymerase II transcription subunit 12 protein (1742-2011AA)

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.

>95%, Protein G purified

Epigenetics and Nuclear Signaling

Recombinant Human Mediator of RNA polymerase II transcription subunit 12 protein (1742-2011AA)