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PINK1 Antibody, FITC conjugated

ArtNr CSB-PA863144LC01HU-50ug
Hersteller Cusabio
Menge 50 ug
Quantity options 100 ug 50 ug
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Konjugat/Tag FITC
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias BRPK antibody,FLJ27236 antibody,mitochondrial antibody,PARK 6 antibody,PARK6 antibody,Phosphatase and Tensin Homolog antibody,PINK 1 antibody,PINK1 antibody,PINK1_HUMAN antibody,Protein kinase BRPK antibody,PTEN induced putative kinase 1 antibody,PTEN induced putative kinase protein 1 antibody,PTEN-induced putative kinase protein 1 antibody,Serine/threonine kinase PINK1 mitochondrial antibody,Serine/threonine protein kinase PINK1 mitochondrial antibody,Serine/threonine-protein kinase PINK1 antibody
Similar products PINK1, Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Targets
PINK1
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias
BRPK antibody, FLJ27236 antibody, mitochondrial antibody, PARK 6 antibody, PARK6 antibody, Phosphatase and Tensin Homolog antibody, PINK 1 antibody, PINK1 antibody, PINK1_HUMAN antibody, Protein kinase BRPK antibody, PTEN induced putative kinase 1 antibody, PTEN induced putative kinase protein 1 antibody, PTEN-induced putative kinase protein 1 antibody, Serine/threonine kinase PINK1 mitochondrial antibody, Serine/threonine protein kinase PINK1 mitochondrial antibody, Serine/threonine-protein kinase PINK1 antibody
Immunogen Species
Human
Immunogen
Recombinant Human Serine/threonine-protein kinase PINK1, mitochondrial protein (162-272AA)
Background
Protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PARK2. Targets PARK2 to dysfunctional depolarized mitochondria through the phosphorylation of MFN2. Activates PARK2 in 2 steps: (1) by mediating phosphorylation at 'Ser-65' of PARK2 and (2) mediating phosphorylation of ubiquitin, converting PARK2 to its fully-active form (PubMed:24660806, PubMed:24751536, PubMed:24784582, PubMed:25527291).
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method
>95%, Protein G purified
General Research Areas
Neuroscience
Initial Research Areas
Neuroscience
Antigen Species
Human
Antigen
Recombinant Human Serine/threonine-protein kinase PINK1, mitochondrial protein (162-272AA)
Clonality
Polyclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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