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HNRNPC Recombinant Monoclonal Antibody

HNRNPC Recombinant Monoclonal Antibody

ArtNr	CSB-RA010605A0HU
Hersteller	Cusabio
Menge	100 ul
Quantity options	100 ul 50 ul
Kategorie	Oncology Infectious Diseases Viral Infections Coronavirus (COVID-19) Antibodies Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot ELISA Immunofluorescence Primary Antibodies By Organ Lung Cancer
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, FC, IF, IP, IHC, ELISA
Clon	9G1
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Heterogeneous nuclear ribonucleoproteins C1/C2, hnRNP C1/C2, HNRNPC, HNRPC
Similar products	HNRNPC, HNRPC, hnRNP C1/C2, Heterogeneous nuclear ribonucleoproteins C1/C2
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Manufacturer - Type	Recombinant Antibody
Manufacturer - Applications	ELISA, WB, IHC, IF, FC, IP; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, IP:1:200-1:1000
Manufacturer - Isotype	Rabbit IgG
Manufacturer - Targets	HNRNPC
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunogen	A synthesized peptide derived from human HNRNPC
Dilution	WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, IP:1:200-1:1000
Background	Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles (PubMed:8264621). Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules (PubMed:12509468, PubMed:16010978, PubMed:7567451, PubMed:8264621). Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides (PubMed:8264621). May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. N6-methyladenosine (m6A) has been shown to alter the local structure in mRNAs and long non-coding RNAs (lncRNAs) via a mechanism named 'm(6)A-switch', facilitating binding of HNRNPC, leading to regulation of mRNA splicing (PubMed:25719671).
Buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method	Affinity-chromatography
General Research Areas	Epigenetics and Nuclear Signaling
Modified	Epigenetics and Nuclear Signaling
Antigen Species	Human
Antigen	A synthesized peptide derived from human HNRNPC
Clonality	Monoclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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CSB-RA010605A0HU-datasheet.pdf

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Menge: 100 ul

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Lieferung vsl. bis 25.09.2025

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