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LMNA Recombinant Monoclonal Antibody

LMNA Recombinant Monoclonal Antibody

ArtNr	CSB-RA013003A0HU
Hersteller	Cusabio
Menge	100 ul
Quantity options	100 ul 50 ul
Kategorie	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Carcinoma Sarcoma Cell Biology Cytoskeleton Flow Cytometry Immunohistochemistry Immunoprecipitation ELISA Immunofluorescence Primary Antibodies Intermediate filaments By Organ Breast Cancer Immunostaining
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	FC, IF, IP, IHC, ELISA
Clon	4H7
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Prelamin-A/C,Lamin-A/C,70 kDa lamin,Renal carcinoma antigen NY-REN-32,LMNA,LMN1
Similar products	LMNA, LMN1, Prelamin-A/C, Lamin-A/C, 70 kDa lamin, Renal carcinoma antigen NY-REN-32
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Manufacturer - Type	Recombinant Antibody
Manufacturer - Applications	ELISA, IHC, IF, FC, IP; Recommended dilution: IHC:1:50-1:200, IF:1:20-1:200, IP:1:200-1:1000
Manufacturer - Isotype	Rabbit IgG
Manufacturer - Targets	LMNA
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunogen	A synthesized peptide derived from human LMNA
Dilution	IHC:1:50-1:200, IF:1:20-1:200, IP:1:200-1:1000
Background	Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation (PubMed:10080180, PubMed:22431096, PubMed:10814726, PubMed:11799477, PubMed:18551513). Required for osteoblastogenesis and bone formation (PubMed:12075506, PubMed:15317753, PubMed:18611980). Also prevents fat infiltration of muscle and bone marrow, helping to maintain the volume and strength of skeletal muscle and bone (PubMed:10587585). Required for cardiac homeostasis (PubMed:10580070, PubMed:12927431, PubMed:18611980, PubMed:23666920).
Buffer	Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Purification Method	Affinity-chromatography
General Research Areas	Cell Biology
Modified	Cell Biology
Antigen Species	Human
Antigen	A synthesized peptide derived from human LMNA
Clonality	Monoclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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CSB-RA013003A0HU-datasheet.pdf

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Menge: 100 ul

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