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Phospho-SMAD2 (S250) Recombinant Monoclonal Antibody

Phospho-SMAD2 (S250) Recombinant Monoclonal Antibody

ArtNr	CSB-RA618017A250phHU-50ul
Hersteller	Cusabio
Menge	50 ul
Quantity options	100 ul 50 ul
Kategorie	Neuroscience Neural Lineage Markers Antibodies Western Blot ELISA Primary Antibodies Neurodegeneration Markers
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, ELISA
Clon	4D12
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Mothers against decapentaplegic homolog 2, MAD homolog 2, Mothers against DPP homolog 2, JV18-1, Mad-related protein 2, hMAD-2, SMAD family member 2, SMAD 2, Smad2, hSMAD2, SMAD2, MADH2, MADR2
Similar products	Smad2, SMAD2, Mothers against DPP homolog 2, SMAD 2, JV18-1, MADH2, hSMAD2, hMAD-2, MADR2, Mothers against decapentaplegic homolog 2, MAD homolog 2, Mad-related protein 2, SMAD family member 2
Lieferbar
Manufacturer - Type	Recombinant Antibody
Manufacturer - Applications	ELISA, WB; Recommended dilution: WB:1:500-1:5000
Manufacturer - Isotype	Rabbit IgG
Manufacturer - Targets	SMAD2
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunogen	A synthesized peptide derived from human Phospho-SMAD2 (S250)
Dilution	WB:1:500-1:5000
Background	Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
Buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method	Affinity-chromatography
General Research Areas	Signal Transduction
Modified	Signal Transduction
Antigen Species	Human
Antigen	A synthesized peptide derived from human Phospho-SMAD2 (S250)
Clonality	Monoclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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CSB-RA618017A250phHU-50ul-datasheet.pdf

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Einfache Bestellung Periodische Bestellung

Menge: 50 ul

lieferbar

Lieferung vsl. bis 21.08.2025