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PTBP1 Recombinant Monoclonal Antibody

ArtNr CSB-RA987652A0HU-50ul
Hersteller Cusabio
Menge 50 ul
Quantity options 100 ul 50 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, IHC, ELISA
Clon 8A1
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Polypyrimidine tract-binding protein 1 (PTB) (57 kDa RNA-binding protein PPTB-1) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I), PTBP1, PTB
Similar products PTBP1, PTB, Polypyrimidine tract-binding protein 1 (PTB) (57 kDa RNA-binding protein PPTB-1) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I)
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Manufacturer - Type
Recombinant Antibody
Manufacturer - Applications
ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200
Manufacturer - Isotype
Rabbit IgG
Manufacturer - Targets
PTBP1
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunogen
A synthesized peptide derived from human PTBP1
Dilution
WB:1:500-1:5000, IHC:1:50-1:200
Background
Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10 (PubMed:15009664). In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:21518806).
Buffer
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method
Affinity-chromatography
General Research Areas
Epigenetics and Nuclear Signaling
Modified
Epigenetics and Nuclear Signaling
Antigen Species
Human
Antigen
A synthesized peptide derived from human PTBP1
Clonality
Monoclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ul
Lieferbar: In stock
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