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Anti-CTLA-4 antibody(DM50); Rabbit mAb

ArtNr DIM-DME100049-100ug
Hersteller DIMA Biotechnology
Menge 100 ug
Quantity options 100 uL 100 ug 10 uL 10 ug 500 ug
Kategorie
Typ Antibody Primary
Format Lyophilized
Applikationen FC, ELISA
Clon DM50
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias CTLA4,CD152
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
Monoclonal antibodies
Manufacturer - Targets
CTLA-4
Molecular Weight
24.6 kDa
Buffer
50% Glycerol; PBS, pH 7.4; 0.1% BSA
Clonality
Monoclonal
Purification
Purified from cell culture supernatant by affinity chromatography
Recommended Dilutions
ELISA 1:5000-10000; Flow Cyt 1:100
Storage
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain; a transmembrane domain; and a cytoplasmic tail. Alternate transcriptional splice variants; encoding different isoforms; have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond; while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus; Graves disease; Hashimoto thyroiditis; celiac disease; systemic lupus erythematosus; thyroid-associated orbitopathy; and other autoimmune diseases.
Immunogen
Recombinant human CTLA4(Gln36-Ser161) (PME100017) produced by using human HEK293 cells
Antigen
CTLA4
Application Advice
ELISA 1/5000-10000; Flow Cyt 1/100
Description
Anti-CTLA-4 antibody(DM50); Rabbit mAb
Preservative
0.1% Procline 300
Reconstitution
Reconstitute with deionized water
Formulation & Reconstitution
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Usage
Research use only

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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