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Anti-B7-H3 antibody(DM53); Rabbit mAb

ArtNr DIM-DME100053-10uL
Hersteller DIMA Biotechnology
Menge 10 uL
Quantity options 100 uL 100 ug 10 uL 10 ug 500 ug
Kategorie
Typ Antibody Primary
Format Lyophilized
Applikationen FC, ELISA
Clon DM53
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias B7-H3,CD276,B7 homolog 3,B7H3
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
Monoclonal antibodies
Manufacturer - Targets
B7-H3
Molecular Weight
57 kDa
Buffer
50% Glycerol; PBS, pH 7.4; 0.1% BSA
Clonality
Monoclonal
Purification
Purified from cell culture supernatant by affinity chromatography
Recommended Dilutions
ELISA 1:5000-10000; Flow Cyt 1:100
Storage
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background
The protein encoded by this gene belongs to the immunoglobulin superfamily; and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors; the protein is preferentially expressed only in tumor tissues. Additionally; it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA; and there is an inverse correlation between the expression of this protein and miR29 levels; suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen
Recombinant human B7H3(Leu29-Pro245) (PME100012) produced by using human HEK293 cells
Antigen
B7H3
Application Advice
ELISA 1/5000-10000; Flow Cyt 1/100
Description
Anti-B7-H3 antibody(DM53); Rabbit mAb
Preservative
0.1% Procline 300
Reconstitution
Reconstitute with deionized water
Formulation & Reconstitution
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Usage
Research use only

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 uL
Lieferbar: In stock
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