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Human CD38 Protein, hFc-His Tag

Human CD38 Protein, hFc-His Tag

ArtNr	DIM-PME100004-10ug
Hersteller	DIMA Biotechnology
Menge	10 ug
Quantity options	100 ug 10 ug 50 ug
Kategorie	Oncology Metabolism Diabetes Glucose Homeostasis By Cell Type Hematology Leukemia Lymphoma Myeloma Peptides & Proteins Recombinant Proteins By Organ Heart & Blood Cancer
Typ	Proteins
Format	Lyophilized
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	HIS, Fc
Purity	The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD38,T10,cADPr hydrolase 1
Similar products	CD38, T10, cADPr hydrolase 1
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	ECD Proteins
Manufacturer - Targets	CD38
Manufacturer - Conjugate / Tag	C-Human Fc and 6xHis Tag
Molecular Weight	The protein has a predicted molecular mass of 70-72 kDa after removal of the signal peptide.
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2 . The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
Molecular Characterization	CD38(Val43-Ile300) hFc(Glu99-Ala330) 6xHis tag
Description	Recombinant human CD38 protein with C-terminal human Fc and 6xHis tag
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Usage	Research use only

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 10 ug

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Lieferung vsl. bis 30.10.2025

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