TGFBR2 Polyclonal Antibody

Primary Antibodies

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

90KDa

This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.

PBS with 0.01% thiomersal, 50% glycerol, pH7.3.

WB 1:500-1:2000; IHC 1:50-1:200

Polyclonal