Syndecan-1 Polyclonal Antibody

Primary Antibodies

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

IHC 1:50-1:200

Polyclonal