CD68 antibody

ArtNr	FNab01491-100ug
Hersteller	FineTest
Menge	100 ug
Quantity options	100 ug 100 ug 100 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Purity	≥95% as determined by SDS-PAGE
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Macrosialin,Gp110,CD68
Lieferbar
Manufacturer - Targets	CD68
Storage Conditions	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Background	This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.
Clonality	polyclonal
Immunogen	CD68 molecule
Observed MW	Refer to figures
Purification	Immunogen affinity purified
Recommended dilution	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Manufacturer - Research Area	Neuroscience, Stem Cells, Immunology, Cancer

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