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Anti-Human CD56 In Vivo Antibody - Low Endotoxin (ERIC-1)

Anti-Human CD56 In Vivo Antibody - Low Endotoxin (ERIC-1)

Hersteller	IchorBio
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Neural Adhesion Molecules Antibodies In Vivo Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Myeloma Sarcoma Adenocarcinoma Immunohistochemistry Western Blot ELISA By Organ Lung Cancer
Typ	Antibody
Specific against	Human
Clon	ERIC-1
Isotype	IgG1
Applikationen	WB, IHC, ELISA
Menge	1mg
Host	Mouse
ArtNr	ICH1015-1MG
Targets	TACC3, NCAM1
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
Aggregation	Aggregation level <= 5%
Antigen Distribution	The CD56 (NCAM) antigen is expressed on most neuroectodermal derived cell lines, tissues, and tumors. NCAM is also known to be expressed on some mesodermally derived tissues such as muscle and on natural killer (NK) lymphocytes. The binding of ERIC-1 to both normal and neoplastic tissue is lost when tissues are conventionally fixed in formalin and embedded in paraffin. The epitope was preserved when exposed to dehydrating fixatives such as cold acetone (-20EC) for 5 min. CD56 is present on 10-25% of peripheral blood lymphocytes.
Application Notes	ELISA Sandwich: This antibody is useful as the capture antibody in a sandwich ELISA. The suggested coating concentration is 80 ng/mL. Dot Blots: Immunoblotting: Recognizes 120, 140, and 180 kDa NCAM isoforms. Each investigator should determine their own optimal working dilution for specific applications.
Background	Anti-Human CD56 can be used in studies of the neural cell adhesion molecule. This antibody may also be used to study isoforms of NCAM expressed on different tumor types. Anti-CD56 (clone ERIC-1) works well in western blot for analysis of isoforms expressed. Anti-CD56 did not react with any of the leukemias or lymphomas tested
Concentration	1.0 - 5.0 mg/ml
Endotoxin	<0.5 EU/mg as determined by the LAL method
Formulation	0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Immunogen	Human Retinoblastoma tumor
Product Type	Low Endotoxin, anti-human
Purification method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Storage	anti-CD56 In Vivo Antibody - Low Endotoxin (ERIC-1) is stable for at least one week when stored sterile at 2-8C. For long term storage aseptically aliquot in working volumes without diluting and store at -80C. Avoid Repeated Freeze Thaw Cycles.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 1mg

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Lieferung vsl. bis 06.06.2024

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