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Anti-ICAM-1 (15.2) In Vivo Antibody - Low Endotoxin Europäischer Partner

ArtNr ICH1027-50MG
Hersteller IchorBio
Menge 50 mg
Quantity options 100 mg 1 mg 25 mg 50 mg 5 mg
Kategorie
Typ Antibody
Applikationen WB, FC, IP, IHC
Clon 15, 2
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG1
Purity >95% by SDS-PAGE and HPLC
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Intercellular adhesion molecule 1, ICAM1, Major group rhinovirus receptor, CD54
Versandbedingung Gekühlt
Lieferbar
Specificity Mouse anti-Human Inter-Cellular Adhesion Molecule 1 (ICAM-1) (Clone 15.2) recognizes an epitope on Human ICAM-1
Manufacturer - Applications
IHC (FFPE), Flow Cytometry, Immunoprecipitation, Western Blot
Manufacturer - Category
Low Endotoxin, monoclonal antibody
Manufacturer - Isotype
Mouse IgG1
Manufacturer - Targets
ICAM-1
Shipping Temperature
Blue ice
Storage Conditions
This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Aggregation
Aggregation level ≤ 5%
Formulation
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution
The CD54 antigen is a membrane glycoprotein with a wide tissue distribution that includes vascular endothelium and many cells of the immune system. CD54 is weakly expressed on resting peripheral blood lymphocytes. Upon activation by mitogens, the CD54 antigen is strongly expressed on B-cells, T-cells, macrophages and granulocytes. CD54 is the receptor for rhinoviruses and malaria.
Application Notes
Each investigator should determine their own optimal working dilution for specific applications.
Background
Intercellular adhesion molecule-1 (ICAM-1) is one of an important cell adhesion molecules (CAMs) family transmembrane glycoprotein and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. ICAM-1 is a marker of endothelial dysfunction leading to damaging vascular disorders, in umbilical and placental vascular tissue of gestational pregnancies.
Concentration
1.0 - 5.0 mg/ml
Endotoxin
<1.0 EU/mg as determined by the LAL method
Manufacturer - Specificity
Mouse anti-Human Inter-Cellular Adhesion Molecule 1 (ICAM-1) (Clone 15.2) recognizes an epitope on Human ICAM-1
Purification method
This monoclonal antibody was purified using Protein A
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Immunogen
Human infant thymocytes and Sezary cells
Antibodies against the same target (Cat No.)
Isotype Control
Mouse IgG1 Isotype Control for In Vivo - Low Endotoxin [HKSP] (ICH2247)
Buffer
ICH3001-100ml; ICH3002-100ml; ICH3003-100ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 mg
Lieferbar: In stock
lieferbar

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