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Antibodies

Anti-Mouse TCR gamma/delta In Vivo Antibody - Low Endotoxin (UC7-13D5) Europäischer Partner

Hersteller IchorBio
Kategorie
Typ Antibody
Specific against Mouse
Clon UC7-13D5
Isotype IgG
Applikationen FC, IP, IV
Menge 100mg
Host Hamster - Armenian
ArtNr ICH1035-100MG
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Manufacturers Product Category
Low Endotoxin, anti-mouse
Target Information
TCR gamma/delta
Isotype Information
Armenian Hamster IgG
Antigen Distribution
gamma/delta TCR expression is observed on a subset of cells in the thymus, intestinal epithelium, skin, liver, peripheral lymphoid tissues, and peritoneum. The gamma/delta TCR is involved in the antigen recognition of some bacterial or tumor-associated antigens presented by MHC class I.
Background
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an alpha and beta chain in 95% of T cells, while 5% of T cells have TCRs consisting of gamma and delta chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.
Immunogen
Unknown
Concentration
≥ 2.0 mg/ml
Formulation
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Aggregation
Aggregation level ≤ 5%
Storage
anti-TCR gamma/delta In Vivo Antibody - Low Endotoxin (UC7-13D5) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Application Notes
In vivo Depletion: This Clone UC7-13D5 has been used for the depletion of TCR gamma/delta T cells in vivo - Each investigator should determine their own optimal working dilution for specific applications.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100mg
Lieferbar: In stock
lieferbar

Lieferung vsl. bis 16.05.2024 

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