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Anti-Mouse CD80 In Vivo Antibody - Low Endotoxin (16-10A1)

Anti-Mouse CD80 In Vivo Antibody - Low Endotoxin (16-10A1)

Hersteller	IchorBio
Kategorie	Antibodies In Vivo Antibodies Western Blot Blocking
Typ	Antibody
Specific against	Mouse
Clon	16-10A1
Isotype	IgG
Applikationen	WB, Blocking
Menge	1mg
Host	Hamster - Armenian
ArtNr	ICH1037-1MG
Targets	CD80
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
Aggregation	Aggregation level <= 5%
Antigen Distribution	Mouse CD80 is expressed on Activated B-Cells, Activated T-Cells, macrophages, and dendritic cells.
Application Notes	Each investigator should determine their own optimal working dilution for specific applications.
Background	CD80 (B7-1) is a type I integral membrane protein related very closely to CD86 (B7-2). A main function of CD80 is the costimulation of T-cells through ligation of CD28 and CD152 (CTLA-4). T-cells activate with binding of CD28 to CD80 and binding of CD80 to CTLA-4 results in inhibition of T-cells. The clone 16-10A1 has the ability to block the costimulatory activity of CD80 while exhibiting no effect on the activity of CD86.
Concentration	1.0 mg/ml
Endotoxin	<= 1.0 EU/mg as determined by the LAL method
Formulation	0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Immunogen	Purified Recombinant Mouse CD80 (>98%)
Product Type	Low Endotoxin, anti-mouse
Purification method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Storage	anti-CD80 In Vivo Antibody - Low Endotoxin (16-10A1) is stable for at least one week when stored sterile at 2-8C. For long term storage aseptically aliquot in working volumes without diluting and store at -80C. Avoid Repeated Freeze Thaw Cycles.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 1mg

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Lieferung vsl. bis 06.06.2024

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