Anti-Mouse CD127 In Vivo Antibody - Low Endotoxin (A7R34)

Low Endotoxin, anti-mouse

anti-CD127 In Vivo Antibody - Low Endotoxin (A7R34) is stable when stored sterile at 2-8C. Do not freeze.

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.

IL-7 receptor alpha (IL-7Ra), also known as CD127, is expressed on bone marrow lymphoid precursors, pro-B cells, monocytes/macrophages, natural killer (NK) cells, naïve T cells and memory CD4+ and CD8+ T cells. IL-7Ra is also expressed on non-immune somatic cells such as intestinal colorectal and renal carcinoma cell lines and keratinocytes. IL-7Ralpha displays a synergistic decrease in the number of T-cell, NK-cell and multipotent progenitors in the thymus, indicating that these distinct survival pathways converge to promote the development of multipotent lymphoid progenitors.

<= 1.0 EU/mg as determined by the LAL method

Products are for research use only. Not for use in diagnostic or therapeutic procedures.