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Anti-CD45R (RA3-6B2) In Vivo Antibody - Low Endotoxin Europäischer Partner

ArtNr ICH1130-1MG
Hersteller IchorBio
Menge 1 mg
Quantity options 100 mg 1 mg 25 mg 50 mg 5 mg
Kategorie
Typ Antibody
Applikationen WB, FC, IF, IP, IHC, ELISA, FA
Clon RA3-6B2
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rat
Isotype IgG2a
Purity >95% by SDS-PAGE and HPLC
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Leukocyte common antigen, L-CA, T200, CD45, Receptor-type tyrosine-protein phosphatase C, PTPRC, B220
Versandbedingung Gekühlt
Lieferbar
Specificity Anti-CD45R In Vivo Antibody - Low Endotoxin (RA3-6B2) recognizes the B-cell determinant (Mr 220 kD) of the CD45 molecule.
Manufacturer - Type
Low Endotoxin, anti-mouse, anti-human
Manufacturer - Applications
Western Blot, Functional Assays, Flow Cytometry, IHC (Frozen), IHC (Paraffin), Immunoprecipitation, Immunofluorescence, ELISA
Manufacturer - Category
Low Endotoxin, anti-mouse, anti-human, monoclonal antibody
Manufacturer - Isotype
Rat IgG2a
Manufacturer - Targets
CD45R
Shipping Temperature
Blue ice
Storage Conditions
Anti-CD45R In Vivo Antibody - Low Endotoxin (RA3-6B2) is stable for at least four (4) weeks when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –80°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Aggregation
Aggregation level ≤ 5%
Formulation
No carrier proteins or preservatives added in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl.
Antigen Distribution
The CD45R antigen is present on mouse B-cells, B-cell precursors, T cell subset, NK cell subsets .
Application Notes
Functional Assay: In vivo treatment with Rat Anti-Mouse CD45R (Clone RA3-6B2) reduces the number of T and B cells and modifies their functional activity.
Each investigator should determine their own optimal working dilution for specific applications.
Background
CD45R, also known as B220 is a 220 kDa transmembrane protein tyrosine phosphatase expressed on B cells and some subsets of T and NK cells. This antibody is commonly used as a B cell marker as CD45R does play a critical role in TCR and BCR signaling.
Concentration
0.5 mg/ml
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Manufacturer - Specificity
Anti-CD45R In Vivo Antibody - Low Endotoxin (RA3-6B2) recognizes the B-cell determinant (Mr 220 kD) of the CD45 molecule.
Purification method
This monoclonal antibody was purified using Protein G
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Immunogen
Abelson murine leukemia virus-induced pre-B tumor cells
Related Antibodies
Antibodies against the same target (Cat No.)
Isotype Control
Rat IgG2a In Vivo Isotype Control - Low Endotoxin [1-1] (ICH2244)
Buffer
ICH3001-100ml; ICH3002-100ml; ICH3003-100ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 mg
Lieferbar: In stock
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