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Anti-Mouse, Human CD45R In Vivo Antibody - Ultra Low Endotoxin (RA3-6B2)

Anti-Mouse, Human CD45R In Vivo Antibody - Ultra Low Endotoxin (RA3-6B2)

Hersteller	IchorBio
Kategorie	Oncology Neuroscience Neural Lineage Markers Antibodies In Vivo Antibodies By Cell Type Carcinoma Hematology Leukemia Western Blot Progenitor Markers
Typ	Antibody
Specific against	Human, Mouse
Clon	RA3-6B2
Isotype	IgG2a
Applikationen	WB, FC, IP, IHC, ELISA, FA
Menge	50mg
Host	Rat
ArtNr	ICH1130UL-50MG
Targets	CD4
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
Manufacturers Product Category	Ultra-Low Endotoxin, anti-mouse, anti-human
Isotype Information	Rat IgG2a
Purification method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution	The CD45R antigen is present on mouse B-cells, B-cell precursors, T cell subset, NK cell subsets .
Background	CD45R, also known as B220 is a 220 kDa transmembrane protein tyrosine phosphatase expressed on B cells and some subsets of T and NK cells. This antibody is commonly used as a B cell marker as CD45R does play a critical role in TCR and BCR signaling.
Immunogen	Abelson murine leukemia virus-induced pre-B tumor cells
Concentration	≥ 2.0 mg/ml
Formulation	No carrier proteins or preservatives added in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl.
Endotoxin	≤ 0.5 EU/mg as determined by the LAL method
Aggregation	Aggregation level ≤ 1%
IMPACT Pathogen Test	We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our rat antibodies are tested for: - Mycoplasma spp - Mycoplasma pulmonis - Pneumonia virus of mice - Kilham's rat virus - Toolan's H1 virus - Rat parvovirus - Lymphocytic choriomeningitis virus - Rat cytomegalovirus - Sendai virus - Rat coronavirus - Sialodacryoadenitis virus - Rat minute virus - Seoul virus - Mouse adenovirus - Reovirus 3 - Rat theilovirus
Storage	anti-CD45R In Vivo Antibody - Ultra Low Endotoxin (RA3-6B2) is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Application Notes	Functional Assay: In vivo treatment with Rat Anti-Mouse CD45R (Clone RA3-6B2) reduces the number of T and B cells and modifies their functional activity. - Each investigator should determine their own optimal working dilution for specific applications.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 50mg

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Lieferung vsl. bis 20.06.2024

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