Hersteller |
IchorBio
|
Kategorie |
|
Typ |
Antibody |
Specific against |
Mouse |
Clon |
RB6-8C5 |
Isotype |
IgG2b |
Applikationen |
WB, FC, IP, IHC, ICC, FA |
Menge |
100mg |
Host |
Rat |
ArtNr |
ICH1131UL-100MG |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Manufacturers Product Category |
Ultra-Low Endotoxin, anti-mouse |
Target Information |
Ly-6G/Ly-6C |
Isotype Information |
Rat IgG2b |
Purification method |
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
Antigen Distribution |
The Gr-1 antigen is present at various levels correlated with granulocyte differentiation and maturation. The Gr-1 antigen is expressed on other myeloid populations, but not on lymphoid or erythroid cells. |
Background |
Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. Clone RB6-8C5 antibody has been shown to inhibit the binding of the clone 1A8 antibody. Clone 1A8 monoclonal antibody reacts specifically with mouse Ly6G with no reported cross-reactivity with Ly6C. |
Immunogen |
Raised against granulocytes of mouse origin |
Concentration |
0.5 mg/ml |
Formulation |
No carrier proteins or preservatives added in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl. |
Endotoxin |
≤ 0.5 EU/mg as determined by the LAL method |
Aggregation |
Aggregation level ≤ 1% |
IMPACT Pathogen Test |
We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our rat antibodies are tested for: - Mycoplasma spp - Mycoplasma pulmonis - Pneumonia virus of mice - Kilham's rat virus - Toolan's H1 virus - Rat parvovirus - Lymphocytic choriomeningitis virus - Rat cytomegalovirus - Sendai virus - Rat coronavirus - Sialodacryoadenitis virus - Rat minute virus - Seoul virus - Mouse adenovirus - Reovirus 3 - Rat theilovirus |
Storage |
anti-Ly-6G/Ly-6C In Vivo Antibody - Ultra Low Endotoxin (RB6-8C5) is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
Application Notes |
Each investigator should determine their own optimal working dilution for specific applications. |
Use |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.