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Mouse Anti-Mouse PD-1 Antibody (RMP1-14) [ICH1182]

Mouse Anti-Mouse PD-1 Antibody (RMP1-14) [ICH1182]

Hersteller	IchorBio
Kategorie	Antibodies Primary Antibodies
Typ	Antibody
Specific against	Mouse
Clon	RMP1-14
Isotype	IgG2a
Applikationen	WB, FC, Blocking, FA
Menge	5mg
Host	Mouse
ArtNr	ICH1182-5MG
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
Manufacturers Product Category	Low Endotoxin, anti-mouse
Target Information	PD-1
Isotype Information	Mouse IgG2a
Purification method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution	Subset of double negative thymocytes, activated T and B cells
Background	CD279, also known as programmed death-1 (PD-1) is a 50-55 kD immunoglobulin superfamily member. PD-1 is expressed on a subset of CD4-CD8- thymocytes, and on activated T and B cells. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. This RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production.
Immunogen	Mouse PD-1 transfected BHK cells
Concentration	1.0 - 5.0 mg/ml
Formulation	0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Aggregation	Aggregation level ≤ 5%
Storage	Mouse anti-mouse PD-1 antibody (RMP1-14) is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -70oC.
Application Notes	Each investigator should determine their own optimal working dilution for specific applications.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 5mg

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Lieferung vsl. bis 06.06.2024

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