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Anti-Mouse Ly49C (4LO3311) In Vivo Antibody - Ultra-Low Endotoxin Europäischer Partner

ArtNr ICH1202UL-50mg
Hersteller IchorBio
Menge 50 mg
Quantity options 100 mg 25 mg 50 mg 5 mg
Kategorie
Typ Antibody Monoclonal
Applikationen FC, IP
Clon 4LO3311
Specific against Mouse (Murine, Mus musculus)
Host Mouse
Isotype IgG3 Kappa
Purity >98% by SDS-PAGE and HPLC
Formula Sterile, preservative-free, solution in PBS. BSA and Azide free.
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Ly-49 inhibitory receptors C
Versandbedingung Gekühlt
Lieferbar
Specificity 4LO3311 activity is directed against Ly49C (Killer cell lectin-like receptor 3, KLRA3; NK2.1). 4LO3311 binds an epitope located in a 32-amino acid segment of the stalk region immediately adjacent to the carbohydrate recognition domain.
Manufacturer - Applications
Depletion, Flow Cytometry, Immunoprecipitation
Manufacturer - Category
Ultra-Low Endotoxin, anti-mouse, monoclonal antibody
Manufacturer - Isotype
Mouse IgG3 Kappa
Manufacturer - Targets
Ly49C
Shipping Temperature
Blue ice
Storage Conditions
This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Aggregation
Aggregation level ≤ 1%
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Antigen Distribution
Ly49C is expressed on NK, uterine NK, NKT, and CD8+ T cells.
Application Notes
Each investigator should determine their own optimal working dilution for specific applications.
Background
4LO3311 recognizes an epitope located in a 32-amino acid segment of the stalk region immediately adjacent to the carbohydrate recognition domain. 4LO3311 recognizes Ly-49CBALB but not Ly-49AB6, Ly-49ABALB, BBALB, DB6, EB6, FB6, GB6, GBALB, or H. 4LO3311 plus complement inhibits NK cell and antibody-dependent cellular cytotoxicity (ADCC) activity in C3H spleen cells4. 4LO3311 inhibits C57BL/6 and C3H NK cell activity but has no effect on NZB NK cells.
Concentration
≥ 2.0 mg/ml
Endotoxin
≤ 0.5 EU/mg as determined by the LAL method
Manufacturer - Specificity
4LO3311 activity is directed against Ly49C (Killer cell lectin-like receptor 3, KLRA3; NK2.1). 4LO3311 binds an epitope located in a 32-amino acid segment of the stalk region immediately adjacent to the carbohydrate recognition domain.
Purification method
This monoclonal antibody was purified using Protein A
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Immunogen
4LO3311 was generated by immunizing 129/SvJ mice with C57BL/6 NK-enriched spleen cells
IMPACT Pathogen Test
We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our hamster antibodies are tested for:
Mycoplasma spp
Mycoplasma pulmonis
Pneumonia virus of mice
Kilham's rat virus
Toolan's H1 virus
Hamster parvovirus
Lymphocytic choriomeningitis
Minute virus of mice
Theiler's murine encephalomyelitis virus
Sendai virus
Reovirus 3
Hantaan virus
Isotype Control
Mouse IgG3 Isotype Control for In Vivo - Low Endotoxin [MG3-35] (ICH2249)
Buffer
ICH3001-100ml; ICH3002-100ml; ICH3003-100ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 mg
Lieferbar: In stock
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