Vergleich

Sutimlimab Biosimilar - Research Grade Europäischer Partner

ArtNr ICH5012-20MG
Hersteller IchorBio
Menge 20 mg
Quantity options 100 mg 10 mg 1 mg 20 mg 50 mg 5 mg
Kategorie
Typ Biosimilars
Applikationen FA
Specific against Human (Homo sapiens)
Isotype IgG4
Purity >95% by SDS-PAGE
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Versandbedingung Gekühlt
Lieferbar
Specificity Detects human C1s. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Sutimlimab. This product is for research use only.
Manufacturer - Applications
Functional Assays
Manufacturer - Category
Low endotoxin, Biosimilar, recombinant antibody
Manufacturer - Isotype
Human IgG4
Manufacturer - Targets
C1s
Shipping Temperature
Blue ice
Storage Conditions
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Background
RUO sutimlimab biosimilar is a humanized monoclonal antibody that is designed to selectively target and inhibit C1s in the classical complement pathway, which is part of the innate immune system. By blocking C1s, sutimlimab inhibits the activation of the classical complement pathway with the goal of halting C1-activated hemolysis in cold agglutinin disease to prevent the abnormal destruction of healthy red blood cells. By selectively inhibiting the classical pathway upstream at C1s, sutimlimab does not inhibit the lectin and alternative complement pathways.
Concentration
5mg/ml
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Manufacturer - Specificity
Detects human C1s. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Sutimlimab.
Purification method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Isotype Control
Bulk Human IgG4 Isotype Control (IB4) [ICH2257]
Buffer
ICH3002

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 mg
Lieferbar: In stock
lieferbar

Vergleichen

Auf den Wunschzettel

Angebot anfordern

Lieferzeit anfragen

Technische Frage stellen

Bulk-Anfrage stellen

Fragen zum Produkt?
 
Schließen