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Theralizumab Biosimilar - Research Grade

Theralizumab Biosimilar - Research Grade

Hersteller	IchorBio
Kategorie	Antibodies In Vivo Antibodies
Typ	Biosimilars
Specific against	Human
Isotype	IgG4
Applikationen	FA
Menge	20mg
ArtNr	ICH5023-20MG
Targets	CD28
eClass 6.1	32160702
eClass 9.0	42030590
Lieferbar
Manufacturers Product Category	Low endotoxin, biosimilar antibody
Isotype Information	Human IgG4
Purification method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background	Theralizumab GN1412 is a humanised monoclonal antibody that not only binds to, but is a strong agonist for, the CD28 receptor of the immune system’s T cells. CD28 is the co-receptor for the T cell receptor; It binds to receptors on the interacting partner in the reaction through one of its ligands (B7 family). It was withdrawn from development after inducing severe inflammatory reactions as well as chronic organ failure in the first-in-human study by PAREXEL in London in March 2006.
Concentration	5mg/ml
Formulation	Sterile, preservative-free, solution in PBS. BSA and Azide free.
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Storage	This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Application Notes	This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 20mg

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Lieferung vsl. bis 20.06.2024

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