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Theralizumab Biosimilar - Research Grade

Theralizumab Biosimilar - Research Grade

ArtNr	ICH5023-20MG
Hersteller	IchorBio
Menge	20 mg
Quantity options	100 mg 10 mg 1 mg 20 mg 50 mg 5 mg
Kategorie	Antibodies In Vivo Antibodies
Typ	Biosimilars
Applikationen	FA
Specific against	Human (Homo sapiens)
Isotype	IgG4
Purity	>95% by SDS-PAGE
Citations	Huang et al. A bispecific antibody AP203 targeting PD-L1 and CD137 exerts potent antitumor activity without toxicity. Journal of Translational Medicine
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	TGN1412, CD28-SuperMAB, TAB08
Versandbedingung	Gekühlt
Lieferbar
Specificity	Detects human CD28. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Theralizumab. This product is for research use only.
Manufacturer - Applications	Functional Assays
Manufacturer - Category	Low endotoxin, Biosimilar, recombinant antibody
Manufacturer - Isotype	Human IgG4
Manufacturer - Targets	CD28
Shipping Temperature	Blue ice
Storage Conditions	This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation	Sterile, preservative-free, solution in PBS. BSA and Azide free.
Application Notes	This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Background	Theralizumab GN1412 is a humanised monoclonal antibody that not only binds to, but is a strong agonist for, the CD28 receptor of the immune system’s T cells. CD28 is the co-receptor for the T cell receptor; It binds to receptors on the interacting partner in the reaction through one of its ligands (B7 family). It was withdrawn from development after inducing severe inflammatory reactions as well as chronic organ failure in the first-in-human study by PAREXEL in London in March 2006.
Concentration	5mg/ml
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Manufacturer - Specificity	Detects human CD28. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Theralizumab.
Purification method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Isotype Control	Bulk Human IgG4 Isotype Control (IB4) [ICH2257]
Buffer	ICH3002

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

ICH5023-20MG-datasheet.pdf

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 20 mg

lieferbar

Lieferung vsl. bis 01.01.2026

Express-Lieferung: 1 Tage sparen

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Bulk-Anfrage stellen

Bestellen Sie passend dazu:

Bulk Human IgG4 (IB4) Isotype Control erfolgreich zu Ihrem Warenkorb hinzugefügt.

Bulk Human IgG4 (IB4) Isotype Control

Auf Anfrage

Menge: 5 mg

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In Vivo Buffer pH7.4 erfolgreich zu Ihrem Warenkorb hinzugefügt.

In Vivo Buffer pH7.4

Auf Anfrage

Menge: 100 ml

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