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Anti-Alpha-fetoprotein (AFP)- Purified - 1.0 mg

ArtNr LEIN-A101-1.0mg
Hersteller Leinco Technologies
Menge 1 mg
Quantity options 1 mg 10 mg 11 mg 250 mg 500 mg
Kategorie
Typ Antibody Monoclonal
Applikationen ELISA
Clon 166
Specific against Human (Homo sapiens)
Host Mouse
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
Primary Monoclonal Antibodies>Tumor Markers
Manufacturer - Targets
Alpha-1 Fetoprotein
Country of Origin
USA
Shipping Temperature
Next Day Ambient
Storage Conditions
This Purified No Carrier Protein antibody is stable when stored at 2-8°C.
Product Description
Alpha-Fetoprotein (AFP) is a significant protein in fetal plasma, playing a crucial role in development. While typically found at low levels in adults, its elevated presence can indicate certain tumors, making it a valuable tumor marker in clinical diagnostics. During fetal development, AFP is primarily produced by the yolk sac and liver, and it's widely considered the fetal equivalent of serum albumin. This versatile protein is known to bind to substances like copper, nickel, fatty acids, and bilirubin, and it can exist in monomeric, dimeric, or trimeric forms, impacting its biological function and detection. Researchers and diagnostic developers rely on high-quality AFP antibodies for accurate detection and quantification in various applications, from cancer research to prenatal screening.
Background
Alpha-1-Fetoprotein (AFP) is a protein that is normally only produced in the fetus during its development. It is a normally produced by the liver and yolk sac of the fetus. AFP levels decrease soon after birth and probably has no function in normal adults. It binds the hormone estradiol to keep it from affecting the fetal brain. Its measurement during pregnancy has been useful to detect certain abnormalities - specifically, if high levels of AFP are found in amniotic fluid, it can indicate a developmental defect in the baby. In some patients who are not pregnant a tumor can produce AFP, thus it can be used as a tumor marker.
PubMed
Alpha-1 Fetoprotein
Manufacturer - Research Area
IVD Raw Material
Manufacturer - Specificity
Mouse Anti-Human Alpha-1 Fetoprotein (AFP) (Clone 166) recognizes Human Alpha-1 Fetoprotein. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
RRID
AB_2828040
Concentration
≥ 5.0 mg/ml
Formulation
This purified antibody is supplied in 0.01 M phosphate buffered saline (PBS), pH 7.4, containing 0.09% sodium azide.
Additional Information
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords
Monoclonal Antibody, Alpha-1 Fetoprotein, 166, AFP, Anti Alpha-1 Fetoprotein, Clone 166, anti-afp, afp antibody

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 mg
Lieferbar: In stock
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