Anti-Rat ALK-7 - 25 µg

IHC FFPE, WB

ALK-7

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Activin receptor-like kinase (ALK) 7 is a type I serine/threonine kinase receptor of the transforming growth factor (TGF)-beta family of proteins.1 ALK7 is most abundantly expressed in human brain, pancreas and colon.2 It negatively regulates glucose-stimulated insulin release in β-cells3 and plays an important role in regulating the functional plasticity of pancreatic islets.3 ALK7 also has an important role in the regulation of body fat deposition. These has implications for the development of treatments against diabetes and obesity.3

IHC (NBF/Par.): This antibody should give satisfactory staining results when used at a concentration of 5-15 µg/mL. The recommended secondary antibody for IHC is PN:G505. For chromogenic detection with high signal and low background use PN:D100 or PN:K107.

Goat Anti-Rat Activin-Receptor-Like Kinase-7 (ALK-7) recognizes Rat ALK-7. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.

This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.

NS0 - Derived Recombinant Rat ALK-7 Extracellular Domain (aa 26 - 108)

Polyclonal Antibody, Activin-Receptor-Like Kinase-7, ALK-7, Rat ALK-7, Anti-Rat ALK-7, activin A receptor, type IC, Activin receptor type IC, activin receptor type-1C, Activin receptor-like kinase 7, Activin RIC, ACTR-IC, ACVR1C, ACVRLK7, ALK7, ALK-7, ALK7ALK-7, EC 2.7.11, EC 2.7.11.30