Anti-Human BMP-9 - 25 µg

ELISA Cap, N, WB

BMP-9

Next Day Ambient

Bone morphogenetic protein (BMP-9) is also known as growth differentiation factor 2 (GDF2) is a protein that in humans encoded by the GDF2 gene. GDF2 belongs to the transforming growth factor beta (TGF-β) superfamily. BMP9 has a role in inducing and maintaining the ability of embryonal and adult tissues. Unlike with other BMP family proteins, the propeptide does not interfere with the biological activity of BMP9 and remains associated with the mature peptide after proteolytic cleavage. Another suggested role of BMP-9 could be a potent inducer of hepcidin in liver cells and could regulate iron metabolism. Mature human and mouse BMP-9 share 96% amino acid sequence identity.

Neutralization: This antibody is useful for neutralization of Human BMP-9 bioactivity. The antibody dose required to neutralize 50% (ND₅₀) of the biological activity of Human BMP-9 (at 5 ng/ml) is 0.01-0.04 µg/ml.

Mouse Anti-Human Bone Morphgenetic Protein 9 (BMP-9) (Clone 360107) recognizes an epitope on Human BMP-9. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.4 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.

Purified Recombinant Human BMP-9 (Accession # Q9UK05)

Monoclonal Antibody, Bone Morphgenetic Protein 9, Growth/Differentiation Factor-2, Clone 360107, BMP-9 , Human BMP-9, Anti-Human BMP-9 (Antigen Aff. Pur.), BMP9, BMP-9, BMP9BMP-9Bone morphogenetic protein 9, GDF2, GDF-2, growth differentiation factor 2, growth/differentiation factor 2