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Anti-Human Chemokine Ligand 23 - 100 µg

ArtNr LEIN-C1412-100ug
Hersteller Leinco Technologies
Menge 100 ug
Quantity options 100 ug 25 ug
Kategorie
Typ Antibody Primary
Applikationen WB
Specific against Human (Homo sapiens)
Host Caprine
Citations 1. Huang, SA. et al. (2007) J Experimental Hematol. 15: 496
2. Woisetschläger, M. et al. (2007) J Immunol 178: 4335
3. Kim, J. et al. (2006) Biochemical and biophysical res communications 340:498
NCBI 6368
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Applications
N, WB
Manufacturer - Category
Polyclonal Antibodies>Growth Factors & Cytokines
Manufacturer - Targets
CCL23
Country of Origin
USA
Shipping Temperature
Next Day Ambient
Storage Conditions
The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Product Description
Chemokine (C-C motif) ligand 23 (CCL23) is a small cytokine belonging to the CC chemokine family.1 It is primarily expressed in cells of the myeloid lineage.2 CCL23 induces endothelial cell migration and tube formation and enhances the expression of MMP-2 mRNA and protein levels in endothelial cells. CCL23 may play a direct role in angiogenesis.3
Background
Chemokine (C-C motif) ligand 23 (CCL23) is a small cytokine belonging to the CC chemokine family.1 It is primarily expressed in cells of the myeloid lineage.2 CCL23 induces endothelial cell migration and tube formation and enhances the expression of MMP-2 mRNA and protein levels in endothelial cells. CCL23 may play a direct role in angiogenesis.3
Other Applications Reported In Literature
Neutralization: This antibody is useful for neutralization of Human Ckβ8-1 bioactivity. The antibody dose required to neutralize 50% (ND50) of the biological activity of Human Ckβ8-1 (at 0.04 ng/ml) is 0.15-0.75 µg/ml.
PubMed
CCL23
Manufacturer - Specificity
Goat Anti-Human Chemokine (C-C Motif) Ligand 23 (CCL23) recognizes Human CCL23. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.
RRID
AB_2828471
Formulation
This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.
Endotoxin Level
< 0.2 EU/µg as determined by the LAL method
Immunogen
E. coli-Derived Human Ckβ8-1
Additional Information
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords
Polyclonal Antibody, Chemokine (C-C Motif) Ligand 23, SCYA23, Ckb-8, Myeloid Progenitor Inhibitory Factor-1 MPIF-1, MIP-3, CKb8, HMRP-2A Human MIP-Related Protein 2A, CCL23, Human CCL23, Anti-Human CCL23, C6 beta-chemokine, CCL23/Ck beta 8-1, chemokine (C-C motif) ligand 23, Ck beta 8-1, CKb8; Ckb-8, Ckb81, CK-beta-8, hmrp-2a, Macrophage inflammatory protein 3, MIP3, MIP-3CK-BETA-8, MPIF1, MPIF-1Ckb-8-1, Myeloid progenitor inhibitory factor 1, SCYA23C-C motif chemokine 23, small inducible cytokine subfamily A Cys-Cys member 23, Small-inducible cytokine A23

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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