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Anti-Mouse CD30 Ligand (Clone 82414) - 25 µg

Anti-Mouse CD30 Ligand (Clone 82414) - 25 µg

ArtNr	LEIN-C1455-25ug
Hersteller	Leinco Technologies
Menge	25 ug
Quantity options	25 ug 500 ug
Kategorie	Antibodies Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Monoclonal
Applikationen	WB, ELISA
Clon	82414
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Citations	1. Croager, EJ. et al. (1997) Biochim. Biophys. Acta. 1353:231 2. Gruss, HJ. et al. (1994) Blood 83:1521 3. Wendtner, CM. et al. (1995) Cancer Res. 55:4157 4. Fischer, M. et al. (2006) J. Clin. Invest. 116:2748 5. Blazar, BR. et al. (2004) J. Immunol. 173:2933
NCBI	21949
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Applications	ELISA Cap, WB
Manufacturer - Category	Primary Monoclonal Antibodies>Growth Factors and Cytokines
Manufacturer - Targets	CD30L
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Product Description	The CD30 ligand is a type II transmembrane glycoprotein of the tumor necrosis factor ligand superfamily. CD30L is expressed on the cell surface of activated T cells, B cells, and monocytes. Recombinant CD30L has been shown to co-stimulate T cells and to act as a mitogen for Hodgkin's disease derived cell lines. The receptor for CD30L, CD30/ TNFRSF8/CD153, is a type I cytokine receptor that is highly expressed by activated T cells, Hodgkin and Reed- Sternberg (H-RS) cells, and anaplastic large cell lymphoma cells. CD30 ligation by CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation and cell death by apoptosis.
Background	The CD30 ligand is a type II transmembrane glycoprotein of the tumor necrosis factor ligand superfamily. CD30L is expressed on the cell surface of activated T cells, B cells, and monocytes. Recombinant CD30L has been shown to co-stimulate T cells and to act as a mitogen for Hodgkin's disease derived cell lines. The receptor for CD30L, CD30/ TNFRSF8/CD153, is a type I cytokine receptor that is highly expressed by activated T cells, Hodgkin and Reed- Sternberg (H-RS) cells, and anaplastic large cell lymphoma cells. CD30 ligation by CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation and cell death by apoptosis.
PubMed	CD30L
Manufacturer - Specificity	Rat Anti-Mouse CD30 Ligand (Clone 82414) recognizes an epitope on Mouse CD30 Ligand. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
RRID	AB_2828518
Formulation	This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Endotoxin Level	< 0.1 EU/µg as determined by the LAL method
Immunogen	Purified Recombinant Mouse CD30 Ligand (> 98%)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, CD30 Ligand, TNFSF8, CD153, 82414, Mouse, Anti-Mouse CD30 Ligand, CD30L, CD153 antigen, CD153, CD30 antigen ligand, CD30 Ligand, CD30L, CD30-L, CD30LCD30 ligand, CD30LGMGC138144, TNFSF8, tumor necrosis factor (ligand) superfamily, member 8, tumor necrosis factor ligand superfamily member 8

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LEIN-C1455-25ug-safety-datasheet.pdf