Anti-Rat MIP-3α - 25 µg

N, WB

MIP-3 alpha

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Macrophage Inflammatory Protein-3 Alpha (MIP3A) also known as CCL20 or liver activation regulated chemokine (LARC) is a small cytokine belonging to the CC chemokine family. It is strongly chemotactic for lymphocytes and weakly attracts neutrophils.1 MIP3A is specifically expressed by the follicle-associated epithelia (FAE) covering intestinal Peyer's patches (PPs) and is the only known chemokine ligand for the chemokine receptor CCR6.2 MIP3-alpha is produced by intestinal epithelial cells (including cells associated with mucosal lymphoid tissues), by keratinocytes in inflamed skin, and by cells in liver and lung.3, 4 It plays an important role in the inflammatory response of blood monocytes and tissue macrophages.

Neutralization:Measured by its ability to neutralize CCL20/MIP‑3 alpha -induced chemotaxis in the BaF3 mouse pro‑B cell line transfected with human CCR6. The Neutralization Dose (ND₅₀) is typically 30-75 µg/mL in the presence of 5 µg/mL Recombinant Rat CCL20/MIP‑3 alpha.

Goat Anti-Rat Macrophage Inflammatory Protein 3 Alpha (MIP-3α) recognizes Rat MIP-3α. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.

This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.

E. coli-Derived Recombinant Rat CCL20

Polyclonal Antibody, MIP-3α, CKb4, Liver Activation Regulated Chemokine, MIP3A, SCYA20, ST38, Exodus-1, MIP-3α, Rat MIP-3α, Anti-Rat MIP-3α, MIP3a, MIP3a antibody, beta chemokine exodus-1, Beta-chemokine exodus-1, CC chemokine LARC, C-C motif chemokine 20, CCL20, chemokine C-C motif ligand 20, CKb4, exodus-1, LARC, LARCLiver and activation-regulated chemokine, MIP3 alpha, MIP-3 alpha, MIP-3a, MIP-3-alpha, MIP3AMacrophage inflammatory protein 3 alpha, SCYA20Small-inducible cytokine A20, small inducible cytokine subfamily A Cys-Cys, member 20, ST38