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Anti-Human CD14 - Biotin - 50 µg

ArtNr LEIN-C154-50ug
Hersteller Leinco Technologies
Menge 50 ug
Quantity options 100 ug 200 ug 50 ug
Kategorie
Typ Antibody Monoclonal
Applikationen FC
Clon UCHM-1
Specific against Human (Homo sapiens)
Host Mouse
NCBI 929
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Applications
Quality Tested by Leinco FC The suggested concentration for this UCHM-1 antibody for staining cells in flow cytometry is ≤ 1.0 μg per 106 cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application.
Manufacturer - Category
Primary Monoclonal Antibodies>SurfaceTag Human CD Markers
Manufacturer - Targets
CD14
Country of Origin
USA
Shipping Temperature
Next Day Ambient
Storage Conditions
This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.
Product Description
CD14 is a 53-55 kD GPI-anchored single chain glycoprotein that plays a role in the clearance of gram-negative pathogens by interacting with other proteins, including TLR-4 and MD-2, to mediate the innate immune response to bacterial lipopolysaccharide (LPS). As a high-affinity receptor for LPS, it is involved in the upregulation of adhesion molecules and cytokine expression in monocytes and neutrophils.
Background
CD14 is a 53-55 kD GPI-anchored single chain glycoprotein that plays a role in the clearance of gram-negative pathogens by interacting with other proteins, including TLR-4 and MD-2, to mediate the innate immune response to bacterial lipopolysaccharide (LPS). As a high-affinity receptor for LPS, it is involved in the upregulation of adhesion molecules and cytokine expression in monocytes and neutrophils.
PubMed
CD14
Ligand/Receptor
LPS
Manufacturer - Research Area
Cell Biology, Immunology, Neuroinflammation, Neuroscience
Manufacturer - Specificity
Clone UCHM-1 recognizes an epitope on human CD14.
RRID
AB_2828609
Concentration
0.5 mg/ml
Formulation
This biotinylated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Antigen Distribution
CD14 is expressed on monocytes, macrophages, dendritic cells, and granulocytes.
Additional Information
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords
Monoclonal Antibody, Cluster of Differentiation 14, P35, UCHM-1, CD14, Human, Anti-Human CD14 (Monocytes)-Biotin

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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