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Anti-Mouse CD3ε (Clone: 500A2) - DyLight® 488 - 200 µg

ArtNr LEIN-C1729-200ug
Hersteller Leinco Technologies
Menge 200 ug
Quantity options 100 ug 200 ug 50 ug
Kategorie
Typ Antibody Monoclonal
Applikationen FC, IHC
Clon 500A2
Specific against Mouse (Murine, Mus musculus)
Host Hamster - Syrian
NCBI 12501
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Applications
FC, IHC FF
Manufacturer - Category
Primary Monoclonal Antibodies>Surfacetag Mouse CD Markers
Manufacturer - Targets
CD3ε
Shipping Temperature
Next Day 2 - 8°C
Storage Conditions
This DyLight® 488 conjugate is stable when stored at 2-8°C. Do not freeze.
Product Description
CD3ε is a 20kDa subunit of the TCR complex and is a transmembrane T-cell surface glycoprotein that belongs to the Ig superfamily. It is one of five polypeptide chains that form the TCR complex by associating with the CD3δ, γ and ζ chains, in addition to the TCR α/β or γ/δ chains. CD3 is involved in TCR signaling, enumeration of immunocompetent T-lymphocytes in peripheral blood, and signal transduction during antigen recognition.
Background
CD3ε is a 20kDa subunit of the TCR complex and is a transmembrane T-cell surface glycoprotein that belongs to the Ig superfamily. It is one of five polypeptide chains that form the TCR complex by associating with the CD3δ, γ and ζ chains, in addition to the TCR α/β or γ/δ chains. CD3 is involved in TCR signaling, enumeration of immunocompetent T-lymphocytes in peripheral blood, and signal transduction during antigen recognition.
Other Applications Reported In Literature
IHC (Frozen) The suggested concentration for this 500A2 antibody in IHC staining on frozen tissue is 5.0 - 10 μg per ml. Titration of the reagent is recommended for optimal performance for each application.
PubMed
CD3ε
Excitation Laser
Blue Laser (493 nm)
Ligand/Receptor
Peptide antigen/MHC-complex.
Manufacturer - Research Area
Cell Biology, Immunology, Signal Transduction
Manufacturer - Specificity
Clone 500A2 recognizes an epitope on mouse CD3ε.
RRID
AB_2828792
Concentration
0.2 mg/ml
Formulation
This DyLight® 488 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Antigen Distribution
CD3ε is primarily expressed on mature T cells and NK-T cells and at different levels on differentiation-dependent thymocytes.
Immunogen
Mouse T cell receptor
Additional Information
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords
Monoclonal Antibody, CD3ε, 500A2, Mouse, Anti-Mouse CD3ε - DyLight® 488

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200 ug
Lieferbar: In stock
lieferbar

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