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Anti-Mouse CD152 (CTLA-4) [Clone 9H10] — DyLight® 550 - 200 µg

Anti-Mouse CD152 (CTLA-4) [Clone 9H10] — DyLight® 550 - 200 µg

ArtNr	LEIN-C1749-200ug
Hersteller	Leinco Technologies
Menge	200 ug
Quantity options	100 ug 200 ug 50 ug
Kategorie	Antibodies Flow Cytometry Primary Antibodies
Typ	Antibody Monoclonal
Applikationen	FC
Clon	9H10
Specific against	Mouse (Murine, Mus musculus)
Host	Hamster - Syrian
NCBI	12477
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Category	Primary Monoclonal Antibodies>Immune Checkpoints\|Primary Monoclonal Antibodies>Surfacetag Mouse CD Markers
Manufacturer - Targets	CTLA-4
Country of Origin	USA
Shipping Temperature	Next Day 2 - 8°C
Storage Conditions	This DyLight® 550 conjugate is stable when stored at 2-8°C. Do not freeze.
Product Description	CTLA-4 is a 33 kD member of the Ig superfamily similar to CD28 in amino acid sequence, structure, and genomic organization. CTLA-4 is a protein receptor that functions as an immune checkpoint and downregulates immune responses. It is involved in the development of protective immunity and thymocyte regulation, in addition to the induction and maintenance of immunological tolerance. CTLA-4 has therapeutic potential both as an agonist to reduce immune activity, and an antagonist to increase immune activity.
Background	CTLA-4 is a 33 kD member of the Ig superfamily similar to CD28 in amino acid sequence, structure, and genomic organization. CTLA-4 is a protein receptor that functions as an immune checkpoint and downregulates immune responses. It is involved in the development of protective immunity and thymocyte regulation, in addition to the induction and maintenance of immunological tolerance. CTLA-4 has therapeutic potential both as an agonist to reduce immune activity, and an antagonist to increase immune activity.
PubMed	CTLA-4
Excitation Laser	Yellow Laser (563 nm)
Ligand/Receptor	CD80 (B7-1), CD86 (B7-2)
Manufacturer - Research Area	Immunology
Manufacturer - Specificity	Clone 9H10 recognizes an epitope on mouse CTLA-4.
RRID	AB_2828814
Concentration	0.2 mg/ml
Formulation	This DyLight® 550 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Antigen Distribution	CTLA-4 is expressed on activated T and B lymphocytes.
Immunogen	Purified Recombinant Mouse CTLA-4 (> 98%)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, Cytotoxic T-Lymphocyte Antigen 4, CD152, CTLA4, 9H10, CTLA-4, Mouse, Anti-Mouse CD152 (CTLA-4) - DyLight® 550

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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LEIN-C1749-200ug-safety-datasheet.pdf