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Anti-Human CD151 - Purified In vivo GOLD™ Functional Grade

ArtNr LEIN-C2039-500ug
Hersteller Leinco Technologies
Menge 500 ug
Quantity options 1 mg 100 mg 25 mg 5 mg 500 ug 50 mg
Kategorie
Typ Antibody Primary
Specific against Human (Homo sapiens)
Host Mouse
Purity ≥95% monomer by analytical SEC, > 95% by SDS Page
Citations 1. Testa, et. al., Cancer Research. 59:3812-3820, 1999
NCBI 977
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Applications
Quality Tested by Leinco FC The suggested concentration for this 50-6 antibody for staining cells in flow cytometry is ≤ 1 μg per 106 cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application.
Manufacturer - Category
Purified in vivo Functional Grade>Gold Purified Bulk Antibodies|Purified in vivo Functional Grade|Primary Monoclonal Antibodies>SurfaceTag Human CD Markers
Manufacturer - Targets
CD151
Country of Origin
USA
Shipping Temperature
Next Day 2-8°C
Storage Conditions
Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Product Description
CD151 is a 29 kD cell surface glycoprotein that is a member of the transmembrane 4 superfamily (tetraspanin family), which is characterized by cell-surface proteins consisting of four hydrophobic domains that mediate signal transduction events involved in the regulation of cell development, activation, growth and motility. CD151 is known to complex with integrins and other transmembrane 4 superfamily proteins and is involved in cell adhesion, migration, and tumor cell metastasis.
Background
CD151 is a 29 kD cell surface glycoprotein that is a member of the transmembrane 4 superfamily (tetraspanin family), which is characterized by cell-surface proteins consisting of four hydrophobic domains that mediate signal transduction events involved in the regulation of cell development, activation, growth and motility. CD151 is known to complex with integrins and other transmembrane 4 superfamily proteins and is involved in cell adhesion, migration, and tumor cell metastasis.
Function
Cell adhesion, migration
Other Applications Reported In Literature
B
CyTOF®
ICC
WB
PubMed
CD151
Ligand/Receptor
CD9, CD181, integrins α3β1, α5β1 and α6β4
Manufacturer - Specificity
Clone 50-6 recognizes an epitope on human CD151.
RRID
AB_2829117
Concentration
≥ 2.0 mg/ml
Formulation
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Product Preparation
Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Antigen Distribution
CD151 is found on immature hematopoietic cells, megakaryocytes, platelets, keratinocytes, epithelial cells, muscle cells, Schwann cells, vascular endothelium, and activated T-cells.
Endotoxin Level
≤ 1.0 EU/mg as determined by the LAL method
Immunogen
Human epidermoid carcinoma cell line HEp-3
Additional Information
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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