Anti-Mouse CD19 [1D3] — FITC - 500 µg

Quality Tested by Leinco B
IP
For specific conjugates of this clone, review literature for suggested application details.

CD19

Next Day 2 - 8°C

CD19 is a 95 kD transmembrane glycoprotein and member of the Ig superfamily. The antigen serves as an adaptor protein; drawing cytoplasmic signaling proteins to the membrane. It works via the CD19/CD21 complex to decrease the threshold for B cell receptor signaling pathways. Because of its presence on all B cells, CD19 is a biomarker for B lymphocyte development, lymphoma diagnosis and can be utilized as a target for the immunotherapy of lymphoproliferative disorders. Emerging studies indicate that CD19 plays an active role in fueling the growth of these cancers, most notably by stabilizing the concentrations of the MYC oncoprotein, making CD19 an attractive therapeutic target with respect to its downstream signaling.

B
IP
For specific conjugates of this clone, review literature for suggested application details.

Blue Laser (490 nm)

Immunology

AB_2829187

This Fluorescein (FITC) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.

Fusion of NS-1 Myeloma cells with spleen cells

Monoclonal Antibody, CD19, B4, CVID3, 1D3, Mouse CD19, Clone 1D3, Flow Cytometry