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Anti-Human CD3 [Clone UCHT-1] — PerCP/Cy5.5 - 100 tests

ArtNr LEIN-C2134-100tests
Hersteller Leinco Technologies
Menge 100 Tests
Quantity options 100 Tests 25 Tests
Kategorie
Typ Antibody Monoclonal
Applikationen FC
Clon UCHT-1
Specific against Human (Homo sapiens)
Host Mouse
Citations 1. van Dongen, J. et al. (1988) Blood 71:603
2. Meuer, SC. et al. (1983) Nature 303:808
3. Beverly, P. et al. (1981) Eur. J. Immunol. 11:329
4. Leukocyte Typing III: Code No. 126, 208 and 471; 4th Workshop: Paper No. T3.2
NCBI 915
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Applications
Quality Tested by Leinco FC The suggested concentration for this UCHT-1 antibody for staining cells in flow cytometry is ≤ .25 μg per 106 cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application.
Manufacturer - Category
Primary Monoclonal Antibodies>SurfaceTag Human CD Markers
Manufacturer - Targets
CD3
Country of Origin
USA
Shipping Temperature
Next Day 2 - 8°C
Storage Conditions
This PerCp/Cy5.5 conjugate is stable when stored at 2-8°C. Do not freeze.
Product Description
CD3ε is a 20kDa subunit of the TCR complex and is a transmembrane T-cell surface glycoprotein that belongs to the Ig superfamily. It is one of five polypeptide chains that form the TCR complex by associating with the CD3δ, γ and ζ chains, in addition to the TCR α/β or γ/δ chains. CD3 is involved in TCR signaling, enumeration of immunocompetent T-lymphocytes in peripheral blood, and signal transduction during antigen recognition.
Background
CD3ε is a 20kDa subunit of the TCR complex and is a transmembrane T-cell surface glycoprotein that belongs to the Ig superfamily. It is one of five polypeptide chains that form the TCR complex by associating with the CD3δ, γ and ζ chains, in addition to the TCR α/β or γ/δ chains. CD3 is involved in TCR signaling, enumeration of immunocompetent T-lymphocytes in peripheral blood, and signal transduction during antigen recognition.
PubMed
CD3
Ligand/Receptor
Peptide antigen bound to MHC
Manufacturer - Research Area
Immunology
Manufacturer - Specificity
Clone UCHT-1 recognizes an epitope on human CD3ε.
RRID
AB_2829216
Concentration
0.1 mg/ml
Formulation
This PerCp/Cy5.5 conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Antigen Distribution
CD3 is expressed on human peripheral blood lymphocytes, splenic lymphocytes, and the majority of T-CLL and T-ALL cells.
Additional Information
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords
Monoclonal Antibody, CD3, UCHT-1, CD3, Human TCR, CD3 Percp/cy5.5

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 Tests
Lieferbar: In stock
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