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Anti-Mouse ICAM-1 (CD54) (Clone BE29G1) - Purified - 500 µg

Anti-Mouse ICAM-1 (CD54) (Clone BE29G1) - Purified - 500 µg

ArtNr	LEIN-C267-500ug
Hersteller	Leinco Technologies
Menge	500 ug
Quantity options	500 ug 50 ug
Kategorie	Antibodies Flow Cytometry Immunohistochemistry Immunoprecipitation Primary Antibodies
Typ	Antibody Monoclonal
Applikationen	FC, IP, IHC
Clon	BE29G1
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
NCBI	15894
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Applications	FC, IHC FF, IP
Manufacturer - Category	Primary Monoclonal Antibodies>Surfacetag Mouse CD Markers
Manufacturer - Targets	Inter-Cellular Adhesion Molecule 1
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	This purified antibody is stable when stored at 2-8°C. Do not freeze.
Product Description	Intercellular adhesion molecule-1 (ICAM-1) is one of an important cell adhesion molecules (CAMs) family transmembrane glycoprotein1 and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines.2 ICAM-1 is a marker of endothelial dysfunction leading to damaging vascular disorders, in umbilical and placental vascular tissue of gestational pregnancies.3
Background	Intercellular adhesion molecule-1 (ICAM-1) is one of an important cell adhesion molecules (CAMs) family transmembrane glycoprotein¹ and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines.² ICAM-1 is a marker of endothelial dysfunction leading to damaging vascular disorders, in umbilical and placental vascular tissue of gestational pregnancies.³
PubMed	Inter-Cellular Adhesion Molecule 1
Ligand/Receptor	CD11a/CD18 (LFA-1) or CD11b/CD18 (Mac-1) and CD11c/CD18, CD43, hyaluronan, fibrinogen
Manufacturer - Research Area	Cell Adhesion, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cell
Manufacturer - Specificity	Rat Anti-Mouse CD54 (Clone BE29G1) recognizes the (Mr 95 kD) cell surface glycoprotein known as intracellular adhesion molecule ICAM-1. ICAM-1 is the receptor for LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18).^{1, 2, 3}
RRID	AB_2829565
Concentration	0.5 mg/ml
Formulation	This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Antigen Distribution	The CD54 antigen is present on endothelial cells, lymphocytes, epithelial cells, dendritic cells and keratinocytes. It has been demonstrated that ICAM-1 enhances T-cell activation.
Immunogen	Purified Recombinant Mouse ICAM-1 (> 98%)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, Inter-Cellular Adhesion Molecule 1, BB2, CD54, P3.58, BE29G1, ICAM-1, Mouse ICAM-1, Anti-Mouse ICAM-1 Purified, Clone BE20G1

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LEIN-C267-500ug-safety-datasheet.pdf