Anti-Human CD57 (Clone VC1.1) - FITC - 50 µg

ArtNr	LEIN-C289-50ug
Hersteller	Leinco Technologies
Menge	50 ug
Quantity options	100 ug 200 ug 50 ug
Kategorie	Oncology Antibodies By Cell Type Hematology Leukemia Lymphoma Flow Cytometry Primary Antibodies
Typ	Antibody Monoclonal
Applikationen	FC
Clon	VC1.1
Specific against	Human (Homo sapiens)
Host	Mouse
NCBI	27087
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Primary Monoclonal Antibodies>SurfaceTag Human CD Markers
Manufacturer - Targets	CD57
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	This Fluorescein conjugate is stable when stored at 2-8°C. Do not freeze.
Product Description	Anti-CD57 may be used in flow cytometry, Western blotting and immunohistology on formalin fixed paraffin embedded tissue sections. The antibody is useful for enumeration of NK subsets and T-lymphocyte subsets, studies of neural tissue, malignant tissues and AIDS-related complex.
Background	Anti-CD57 may be used in flow cytometry, Western blotting and immunohistology on formalin fixed paraffin embedded tissue sections. The antibody is useful for enumeration of NK subsets and T-lymphocyte subsets, studies of neural tissue, malignant tissues and AIDS-related complex.
PubMed	CD57
Excitation Laser	Blue Laser (490 nm)
Ligand/Receptor	Binds to L-selectin and P-selectin in a calcium-dependent manner, also binds to second globular domain of E8 laminin fragment.
Manufacturer - Research Area	Costimulatory Molecules, Immunology
Manufacturer - Specificity	Mouse Anti-Human CD57 (Clone VC1.1) recognizes Human CD57. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Anti-CD57 recognizes a (Mr 110 kD) carbohydrate molecule on myeloid cells. This surface antigen is associated with myelin-associated glycoprotein (MAG).¹ This antibody blocks binding of HNK-1 (Leu. 7) antibody.³
RRID	AB_2829619
Concentration	0.2 mg/ml
Formulation	This Fluorescein (FITC) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Antigen Distribution	The CD57 antigen is present on 15-20% of normal peripheral blood mononuclear cells. It is expressed on a subset of natural killer cells (60%) and on a subset of T-lymphocytes. This carbohydrate is also present on N-CAM in the nervous system.
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, CD57, HNK-1, Natural Killer Cells, VC1.1, CD57, Human CD57, Anti-Human CD57 - FITC, Flow Cytometry

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LEIN-C289-50ug-safety-datasheet.pdf