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Anti-Mouse CXCL16 - 25 µg

Anti-Mouse CXCL16 - 25 µg

ArtNr	LEIN-C451-25ug
Hersteller	Leinco Technologies
Menge	25 ug
Quantity options	100 ug 25 ug
Kategorie	Antibodies Flow Cytometry Western Blot Primary Antibodies
Typ	Antibody Primary
Applikationen	WB, FC
Specific against	Mouse (Murine, Mus musculus)
Host	Caprine
Citations	1. Mummidi, S. et al. (2004) J Biol Chem. 279:3188 2. Adams, DH. et al. (2005) J Immunol. 174:1055 3. Clinman, DM. et al. (2006) J Immunol. 177:1575 4. Broedl, UC. et al. (2008) Scand J Gastroenterol. 43:283
NCBI	66102
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Applications	CyTOF®, FC, N, WB
Manufacturer - Category	Polyclonal Antibodies>Growth Factors & Cytokines
Manufacturer - Targets	CXCL16
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Product Description	Chemokine (C-X-C motif) ligand 16 (CXCL16), also known as SR-PSOX, is a transmembrane protein that facilitates uptake of low density lipoproteins by macrophages, resulting in foam cell formation.1 CXCL16 is found in liver tissue2 and influences the uptake, subcellular localization, and cytokine profile induced by D oligonucleotides.3 CXCL16 may play a pro-inflammatory role in Inflammatory Bowel Disease (IBD), particularly Crohn's disease.4
Background	Chemokine (C-X-C motif) ligand 16 (CXCL16), also known as SR-PSOX, is a transmembrane protein that facilitates uptake of low density lipoproteins by macrophages, resulting in foam cell formation.¹ CXCL16 is found in liver tissue² and influences the uptake, subcellular localization, and cytokine profile induced by D oligonucleotides.³ CXCL16 may play a pro-inflammatory role in Inflammatory Bowel Disease (IBD), particularly Crohn's disease.⁴
Other Applications Reported In Literature	Neutralization: This antibody is useful for neutralization of Mouse CXCL16 bioactivity. The antibody dose required to neutralize 50% (ND₅₀) of the biological activity of Mouse CXCL16 (at 7.5 ng/ml) is 0.1 - 0.4 µg/ml. CyTOF-ready: Suitable for use at concentration ofReady to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
PubMed	CXCL16
Manufacturer - Research Area	Chemokine
Manufacturer - Specificity	Goat Anti-Mouse CXCL16 recognizes Mouse CXCL16. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.
RRID	AB_2829724
Formulation	This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.
Endotoxin Level	< 0.1 EU/µg as determined by the LAL method
Immunogen	Purified Recombinant Mouse CXCL16 (> 98%)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Polyclonal Antibody, Chemokine (C-X-C Motif) Ligand 16, SCYB16, SR-PSOX, CXCLG16, Zmynd15, AV290116, BB024863, 0910001K24Rik, CXCL16, Mouse CXCL16, Anti-Mouse CXCL16, chemokine C-X-C motif ligand 16, CXC chemokine ligand 16, CXCL16, CXCLG16, Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein, SCYB16, Small-inducible cytokine B16, SRPSOXC-X-C motif chemokine 16, SR-PSOXTransmembrane chemokine CXCL16

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LEIN-C451-25ug-safety-datasheet.pdf