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Anti-Mouse/Rat CD71 - Purified in vivo GOLD™ Functional Grade

ArtNr LEIN-C853-100mg
Hersteller Leinco Technologies
Menge 100 mg
Quantity options 1 mg 100 mg 25 mg 5 mg 50 mg
Kategorie
Typ Antibody Monoclonal
Applikationen FC, IHC, IV
Clon OX-26
Specific against Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG2a kappa
Purity ≥95% monomer by analytical SEC, >95% by SDS Page
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Category
Purified in vivo Functional Grade>Gold Purified Bulk Antibodies|Purified in vivo Functional Grade|Primary Monoclonal Antibodies>SurfaceTag Human CD Markers
Manufacturer - Targets
CD71
Shipping Temperature
Next Day 2-8°C
Storage Conditions
Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Product Description
CD71 is a transferrin receptor on the cell surface that mediates the uptake of transferrin-iron complexes, thereby mediating cellular proliferation1. CD71 is a homodimeric glycoprotein containing 760 amino acids and it binds to diferric transferrin2. Binding by diferric transfferin causes CD71 to be internalized, and diferric iron is subsequently released3. CD71 is highly expressed on malignant cells, as iron uptake is necessary for aberrant cell proliferation4.
Concentration
≥ 5.0 mg/ml
Formulation
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.0-7.5, 0.005% pS80 stabilizing buffer, with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Antigen Distribution
CD71 is expressed on the surface of proliferating cells, reticulocytes, and erythroid precursors.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 mg
Lieferbar: In stock
lieferbar

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